Suggestions for mild cam & muiltple carb setup with Columbia rearend

[flathead47]

Looking for some input. I am installing a Columbia in my 47 Ford convertible , it has a Edelbrock 3 x 2 carb intake with three 94's installed , only the centre carb operating , other 2 carbs blocked off. I am not sure what cam is installed in the motor , but would like to install a mild street cam with a working muiltiple carb setup , 2 x 2 or use the existing 3 x 2 setup , 97's or 94's. Do I need to worry about vacuum levels with the mild street cam & Columbia operation. What recommendations / setups are you using with your Columbia ? Thanks